Why choose Nizoral® shampoo?

Nizoral® helps treat the cause of dandruff, not just the symptoms. Nizoral® contains Ketoconazole which targets the root cause of dandruff. 

Targets the root cause of dandruff and not just the symptoms*

Clinically proven efficacy to control itching and flaking**

Suitable for all hair types

Dermatologically tested and fragrance-free***

Nizoral® shampoo

A clinically proven solution containing Ketoconazole, which effectively combats the fungus (yeast) that causes dandruff and quickly relieves itching and flaking.*

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What is dandruff?

Dandruff is not always a common chronic skin condition, it can also be a temporary issue that occurs when the body goes through hormonal changes such as puberty. As the scalp is typically covered in hair and we can’t see the exact condition of our skin, dandruff manifests itself by white flakes of dead skin that fall from the  scalp. 

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Nizoral® dandruff shampoo and Nizoral® anti-dandruff shampoo use Ketoconazole to help treat and prevent dandruff.
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Nizoral® frequently asked questions

  • How does Nizoral® work?

    Nizoral with Ketoconazole may help treat the fungus (yeast) which can cause dandruff, thereby helping to relieve itching and flaking.

  • How do I use Nizoral® shampoo?

    Nizoral can be used for both treatment and prevention.

    Rinse your hair with water and then wash the affected areas with a small amount of the shampoo. Leave on the hair for 3-5 minutes before rinsing thoroughly. Always wash your hands thoroughly afterwards. Check the instructions with the bottle check to see how many times a week to use as this will depend on your condition and whether you are treating or preventing dandruff.

  • What is Ketoconazole and how does it work?

    Ketoconazole works by stopping the growth of the fungus (yeast) which is the major cause of dandruff on the scalp. It helps to protect the scalp from further outbreaks by binding to the natural proteins of the hair.****

  • How long after using Nizoral® should I see results?

    Nizoral starts working from the first wash and can show visible results in 2 weeks.***** If your scalp has not cleared after 4 weeks, you may not have dandruff and should seek further advice from your pharmacist or doctor.*****

  • What’s the difference between dandruff and seborrhoeic dermatitis?

    The cause of dandruff is a naturally occurring microbe on the scalp called Malassezia furfur. Symptoms include flaking and itching of the scalp. Dandruff affects up to 50% of the population at some point in their lives.******

    Seborrhoeic dermatitis is a far more severe form of dandruff. It shares most of its symptoms with dandruff but in addition, scaling on scalp, yellow flake scales, inflamed areas, appearance on other body areas. Seborrhoeic dermatitis is estimated to affect up to 5% of adults.

  • What are the main causes of dandruff?

    Dandruff is far more common than people think. It isn’t caused by poor hygiene but can be more noticeable without regular hair washing. Many factors can contribute to a build-up of dandruff such as stress and hair styling products, but the main causes of dandruff are:

    Malassezia is a group of fungi (yeast) that naturally occurs on the skin surface of humans. One of these fungi species is Malassezia furfur. The fungus (yeast) needs fat to grow and can be found on sebaceous skin and hairy areas of the body such as the scalp, face, chest and back.

    Tinea Capitis
    Tinea capitis is a fungal infection that affects the scalp. It is sometimes also known as scalp ringworm, as it can cause a scaly, red rash. Tinea capitis can affect both adults and children but is more common in children.

    Eczema is a skin condition that causes the skin to become itchy, red, dry and cracked. Eczema can affect any part of the body, but most often affects the hands, creases of elbows and knees, face and scalp, when the scalp is affected it can lead to dandruff.

    Psoriasis is a skin condition that is associated with red, flaky, patches of skin that look like they are covered with silvery scales. These patches can appear anywhere on your body but can often affect the scalp, which can cause dandruff. Psoriasis affects around 2% of people in the UK and can start at any age.

    Allergic Contact Dermatitis
    Allergic contact dermatitis is an allergic reaction to contact with a particular substance such as soap or detergent and usually occurs within a few hours or days of exposure to an allergen or an irritant. This reaction can cause the skin on the scalp to become red, blistered, dry and cracked.


*/***Summary of Product characteristics (SPC) of Nizoral 2% shampoo, UK (2015) and SPC of Terzolin 2% Lösung, Germany (2015).
Borda LJ and Wikramanayake TC. Seborrheic Dermatitis and Dandruff: A Comprehensive Review. J Clin Investig Dermatol 2015. December; 3(2).
Hay RJ. Malassezia dandruff and seborrhoeic dermatitis: an overview. Br J Dermatol. 2011;
165(Suppl 2):2–8.
Bergler, R.; Mills Jr., O.H.; Jones, E.L.; Mrusek, S. Double-blind, placebo-controlled trial of ketoconazole 2% shampoo in the treatment of moderate to severe dandruff. Advances in therapy. 1990; 7(5): 247-256.
**Ketoconazole 2% shampoo has been studied extensively in more than 2,000 patients with dandruff or Seborrhoeic dermatitis. Compared to placebo, the shampoo has been consistently more effective.
Van Cutsem J., Van Gerven F., Fransen J., Schrooten P., and Janssen PAJ. The in vitro antifungal activity of ketoconazole, zinc pyrithone, and selenium sulphide against Pityrosporum and their efficacy as a shampoo in the treatment of experimental pityrosporum in guinea pigs. J Am Acad Dermatol 1990:22 (No. 6 Pt 1): 993-998. 
Sanfilippo A and English JC. An overview of Medicated Shampoos used in Dandruff Treatment. P&T (2006), 31(7): 396-400.
Danby FW, Maddin S, Margesson LJ, and Rosenthal D. A randomized, double-blind, placebo-controlled trial of ketoconazole 2% shampoo versus selenium sulfide 2.5% shampoo in the treatment of moderate to severe dandruff. J Am Acad Dermatol. (1993), 29(6):1008-1012.
Billhimer WL, Bryant PB, Murray KP, Coffindaffer TW, Rains GY, Amon RB, Hickman JG and Reed BR. Results of clinical trial comparing 1% pyrithione zinc and 2% ketoconazole shampoos. Cosmet Dermatol. (1996);9(5):34-39.
Ive FA. An overview of experience with ketoconazole shampoo. BJCP, WINTER 1991. VOL 45 NO 4.
***Most of the studies have been carried out by dermatologists and in departments of dermatological clinics universities so that ketoconazole is dermatologically tested in great detail. 
Borda LJ and Wikramanayake TC. Seborrheic Dermatitis and Dandruff: A Comprehensive Review. J Clin Investig Dermatol 2015. December; 3.
Hay RJ. Malassezia dandruff and seborrhoeic dermatitis: an overview. Br J Dermatol. 2011; 165(Suppl 2):2–8.
Pierard GE, Arrese JE, Pierard-Franchimont C, DE Doncker P. Prolonged effects of anti-dandruff shampoos - time to recurrence of Malassezia ovalis colonization of skin. Int J Cosmet Sci. 1997;19(3):111–117. 
****Dobrev H and Zissova L. Effect of ketoconazole 2% shampoo on scalp sebum level in patients with seborrhoeic dermatitis. Acta Derm Venereol. 1997;77(2):132–134. 
Del Rosso JQ. Adult Seborrheic Dermatitis. A Status Report on Practical Topic Management. J of Clinical Asthetic Dermatology (2011), 4 (5):32-38. 
Piérard-Franchimont C,Goffin V, Decroix J and PiérardG,E. A Multicentre Randomized Trial of Ketoconazole 2% and Zinc Pyrithione 1% Shampoos in Severe Dandruff and Seborrheic Dermatitis. Skin Pharmacol Appl Skin Physiol 2002; 15:434-441. 
Pierard GE, Arrese JE, Pierard-Franchimont C, DE Doncker P. Prolonged effects of anti-dandruff shampoos - time to recurrence of Malassezia ovalis colonization of skin. Int J Cosmet Sci. 1997;19(3):111–117.
*****Pierard-Franchimont et al.2001_Dermatology_2001;202:171-176 (25) shows the effect of the 2% product measured after 2 and 4 weeks. 
******BORDA LJ and WIKRAMANAYAKE TC (2015) Seborrheic dermatitis and dandruff: A comprehensive review. J Clin Investig Dermatol 3(2);10.13188/2373-1044.1000019.
*******NICE (2021) Seborrhoeic dermatitis. Clinical Knowledge Summary.