Prescription strength antimalarial protection. Now available without a prescription

Find in store

With Maloff protect (atovaquone 250 mg / proguanil 100mg) it has never been easier to protect yourself against malaria. A form of malaria chemoprophylaxis, this malaria prevention medication is now available to buy over-the-counter.

You don’t need a prescription from a doctor for Maloff protect, and it’s available direct from LloydsPharmacy. Just another way that we can make your travel experience a little bit easier.

Maloff protect is available in two pack sizes:

24 tablets - ideal if you are travelling for 1-2 weeks
36 tablets - ideal if you are travelling for longer than two weeks

Maloff Protect frequently asked questions

  • How does Maloff Protect work?

    Maloff Protect is a form of malaria chemoprophylaxis (also known as antimalarial) – a preventative medication which travellers can take to fight against infection.

    The P. falciparum parasite this is the most serious form of human malaria and is responsible for 99% of associated deaths.* Maloff Protect contains ingredients atovaquone and proguanil, which both work to halt the production of the P. falciparum parasite after it has entered the bloodstream.

    Atovaquone works to stop the production of substances needed for the parasites’ reproduction and Proguanil hydrochloride inhibits the action of a compound that is found in the parasite.

  • How quickly does Maloff Protect work?

    To be effective, you need to take Maloff Protect one to two days before you start your travels, every day of your stay and seven days after your return to a malaria-free area.

    Maloff Protect works by killing the Plasmodium parasite and stopping it spreading. After being bitten, it takes up to seven days for Maloff Protect to kill the malarial parasites in your bloodstream. If it is taken incorrectly or the course is not completed, you place yourself at an increased risk of malaria infection. There are no other commonly used antimalarial drugs that offer a shorter period of medication. Maloff Protect is particularly convenient for those last-minute travellers!

  • Who can take Maloff Protect?

    Maloff Protect is only suitable for people who are aged 18 years or over and weigh more than 40 kg (6st 4lbs).

    If you fall into any of the groups below (or any others pointed out in the patient information leaflet), then speak to one of our in store pharmacists about other forms of malaria prevention:

    • Children and adolescents
    • Adults weighing less than 40 kg
    • People allergic to any of the ingredients (see information leaflet for more details)
    • Women who are pregnant, breastfeeding or trying to become pregnant
  • Which pack size is right for me?

    Maloff Protect tablets come in a variety of pack sizes to suit your stay. So whether you are on holiday for a week or planning to travel for months, you can ensure you are protected for the duration of your trip. Use the table below to work out how many tablets you require with how many packs you will need to buy to cover this.

    Days in malaria area Total number of tablets Recommended pack size
    7 (1 week) 16 1 x 24
    14 (2 weeks) 23 1 x 24
    21 (3 weeks) 30 1 x 36
    28 (4 weeks) 37 2 x 24
    42 (6 weeks) 51 1 x 36, 1 x 24
    56 (8 weeks) 65 2 x 36
    84 (12 weeks) 93 2 x 36, 1 x 24


    Maloff Protect is available in pack sizes of 24 or 36 tablets.

  • How to take Maloff Protect?

    Maloff Protect is really easy to take as you only need to take one Maloff Protect tablet:

    • One to two days before you start your travels
    • Every day during your stay in the malarial region
    • For seven days upon your return to a malaria-free area

    During this course of Maloff protect, ensure:

    • You take the tablet at the same time each day, e.g. in the morning when you wake up
    • With food to aid absorption
    • Do not crush the tablet, it must be swallowed whole for best results
    • If you happen to vomit within one hour of taking Maloff Protect, be sure to take another tablet straight away
    • If you forget to take a dose, just continue the course as planned. Do not take two tablets together as this may increase your chance of experiencing side effects

    Be sure to read the instructions in the patient information leaflet carefully, and download the Maloff Protect Reminder App.

  • What are the possible side effects of Maloff Protect?

    Just like all medicines, some people may experience side effects whilst taking Maloff Protect. If you experience side effects, speak to one of our in store pharmacists or let your doctor know.

    The most common side effects are:

    • Headaches
    • Nausea and vomiting
    • Diarrhoea and abdominal pain

    Severe reactions are rare, but if any are experienced stop taking the medication immediately and consult your doctor.

    Rare side effects are:

    • Skin rashes and itching
    • Sudden wheezing
    • Difficulty breathing
    • Swelling of the face
    • Tightening of the chest or throat
  • How to buy Maloff Protect online?

    Maloff Protect is available to order online at LloydsPharmacy. You will have to answer a few quick questions so that we can check your suitability, but when you are approved, you can have it delivered straight to your home or for pick up at your local store. Feel free to pop into store anytime to ask one of our pharmacists any questions you may have about Maloff Protect.

    Don’t forget to enter your travel details into our  Vaccination Checker  for up-to-date travel vaccination and antimalarial recommendations. Just another way that we can help you prepare for your trip.

    Along with your tailored results you will receive a recommend diet, practical sample menus and portion size guides to help you make better choices to support weight loss. You will also receive genetic insights about your BMI, weight and appetite control to help you be the best possible you.

  • Other ways to protect yourself against Malaria

    When travelling to a malarial region of the world, you should take every step to avoid getting bitten by mosquitos. Taking a preventative medication like Maloff Protect is just one step towards optimised protection:

    Protect yourself against Malaria
  • What is malaria?

    Malaria is a tropical disease that is potentially very serious but preventable. Caused by a parasitic infection spread by mosquito bites, it is one of the major causes of illness, and even death, in the tropical regions of the world. Malaria may be caused by a different type of parasite depending on which region(s) you visit. There are a total of four types of human malaria.

    Symptoms include:

    • Fever
    • Chills
    • Sweats
    • Dizziness
    • Diarrhoea
    • Vomiting
    • Muscular aching
    • Muscle weakness

    It only takes a single bite for someone to become infected.

    Anyone can contract malaria, from first-time travellers to those born in a malarial region who are returning to visit. Everyone should take precautions to protect themselves.

  • What countries are at risk?

    Malaria is prevalent in in tropical and subtropical regions such as Africa and Asia. Despite the decreasing numbers of transmissions and deaths, malaria remains a serious illness.

    Malaria risk map

    That’s why it is important that you chose a antimalarial medication dependent on:

    • What malarial region you visit
    • How many countries you travel to
    • The level of resistance to antimalarial drugs in those regions

    Your malaria chemoprophylaxis (antimalarial) needs to offer protection for all locations you visit and it is vital that you ensure the full course of medication is completed.

  • Remember to keep up to date

    The regions affected by malaria continually change over time and by season, plus there is a rising resistance to antimalarial medication. It is important that you keep up to date with the latest travel news and advice.

    Enter your travel details into our  vaccination checker  for up-to-date travel vaccination and antimalarial recommendations.

  • Other ways to protect yourself against malaria

    When travelling to a malarial region of the world, you should take every step to avoid getting bitten by mosquitos. Taking a preventative medication like Maloff Protect is just one step towards optimised protection.

  • How to prevent mosquito bites:

    • Keep your skin covered and wear loose fitting clothing
    • If you have any exposed skin, like your face and neck, apply insect repellent – preferably it needs to contain over 20% DEET
    • Screen the windows and doors of your accommodation
    • Cover your bed with a mosquito net for sleeping – for better results, the net should be treated with insecticide
    • Make sure all windows and doors are shut at sunset and during the night – use air conditioning or a fan to keep you cool
  • What to do if you think you have malaria

    Malaria can affect anyone, and some types of Malaria can take longer to develop. It is it’s possible for symptoms to not be experienced until several months after returning home.

    If you are taking medication, are pregnant or breast feeding, or have other health conditions, we recommend that you discuss a healthcare professional before you make any lifestyle or dietary changes.

    See a doctor immediately if you think you might have malaria and experience the following:

    • A high temperature (fever) and sweats
    • Headaches
    • Weakness and fatigue
    • Chills and shivering
    • Vomiting and nausea


*World Health Organisation. World Malaria Report 2016.
PIL for non prescription atovaquone/proguanil 250 mg/100 mg.